17b-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-a pathway
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چکیده
SANJAY CHANDA,1 C. LEE ROBINETTE,1,2 JOHN F. COUSE,3 AND ROBERT C. SMART1 1Molecular and Cellular Toxicology, Department of Toxicology, and 2Department of Anatomy, Physiological Sciences and Radiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27695; and 3Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709
منابع مشابه
An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.
The hair follicle is a cyclic, self renewing epidermal structure which is thought to be controlled by signals from the dermal papilla, a specialized cluster of mesenchymal cells within the dermis. Topical treatments with 17-beta-estradiol to the clipped dorsal skin of mice arrested hair follicles in telogen and produced a profound and prolonged inhibition of hair growth while treatment with the...
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تاریخ انتشار 2000